tblNCA.Rddo multiple NCA and returns a result table.
tblNCA(concData, key = "Subject", colTime = "Time", colConc = "conc", dose = 0, adm = "Extravascular", dur = 0, doseUnit = "mg", timeUnit = "h", concUnit = "ug/L", down = "Linear", MW = 0, returnNA = FALSE)
| concData | concentration data table |
|---|---|
| key | column names of concData to be shown at the output table |
| colTime | column name for time |
| colConc | column name for concentration |
| dose | administered dose |
| adm | one of |
| dur | duration of infusion |
| doseUnit | unit of dose |
| timeUnit | unit of time |
| concUnit | unit of concentration |
| down | method to calculate AUC, |
| MW | molecular weight of drug |
| returnNA | if |
Basically same with sNCA
help, sNCA
tblNCA(Theoph, key="Subject", dose=320, concUnit="mg/L")#> ID b0 CMAX CMAXD TMAX TLAG CLST #> [1,] "1" "2.36878509420585" "10.5" "0.0328125" "1.12" "0" "3.28" #> [2,] "2" "2.41123733696293" "8.33" "0.02603125" "1.92" "0" "0.9" #> [3,] "3" "2.52971150145858" "8.2" "0.025625" "1.02" "0" "1.05" #> [4,] "4" "2.59275546723663" "8.6" "0.026875" "1.07" "0" "1.15" #> [5,] "5" "2.55109229061238" "11.4" "0.035625" "1" "0" "1.57" #> [6,] "6" "2.0334043955261" "6.44" "0.020125" "1.15" "0" "0.92" #> [7,] "7" "2.28854976005424" "7.09" "0.02215625" "3.48" "0" "1.15" #> [8,] "8" "2.17040271754659" "7.56" "0.023625" "2.02" "0" "1.25" #> [9,] "9" "2.12464810390587" "9.03" "0.02821875" "0.63" "0" "1.12" #> [10,] "10" "2.65770546248091" "10.21" "0.03190625" "3.55" "0" "2.42" #> [11,] "11" "2.1475943307927" "8" "0.025" "0.98" "0" "0.86" #> [12,] "12" "2.82449347826545" "9.75" "0.03046875" "3.52" "0" "1.17" #> CLSTP TLST LAMZHL LAMZ #> [1,] "3.28014647414312" "24.37" "14.304377571097" "0.0484569969657749" #> [2,] "0.888639849106919" "24.3" "6.65934156262252" "0.104086443688432" #> [3,] "1.05509670837553" "24.17" "6.76608737718236" "0.102444314109434" #> [4,] "1.15642160174997" "24.65" "6.98124666099893" "0.0992870205306231" #> [5,] "1.55569511595616" "24.35" "8.0022640410078" "0.0866188839818201" #> [6,] "0.941271173708175" "23.85" "7.89499786796582" "0.0877957400561702" #> [7,] "1.16071921229933" "24.22" "7.84666826130148" "0.0883364961379133" #> [8,] "1.22852675835656" "24.12" "8.51003788342506" "0.0814505399453019" #> [9,] "1.11648311706515" "24.43" "8.40599880716182" "0.0824586341803179" #> [10,] "2.41369227401111" "23.7" "9.24691582297898" "0.0749598237757766" #> [11,] "0.859806606884089" "24.08" "7.26123651504339" "0.0954585598642772" #> [12,] "1.17553904959565" "24.15" "6.28650816367189" "0.110259489451627" #> LAMZLL LAMZUL LAMZNPT CORRXY R2 #> [1,] "9.05" "24.37" "3" "-0.99999986483748" "0.999999729674979" #> [2,] "7.03" "24.3" "4" "-0.998596709529913" "0.99719538828397" #> [3,] "9" "24.17" "3" "-0.999662423945811" "0.999324961849213" #> [4,] "9.02" "24.65" "3" "-0.999461923749821" "0.998924137025692" #> [5,] "7.02" "24.35" "4" "-0.999323363372814" "0.998647184582752" #> [6,] "2.03" "23.85" "7" "-0.999120281624298" "0.998241337153017" #> [7,] "6.98" "24.22" "4" "-0.999334862622512" "0.998670167652754" #> [8,] "3.53" "24.12" "6" "-0.995496052943785" "0.991012391426654" #> [9,] "8.8" "24.43" "3" "-0.99972179371205" "0.999443664822839" #> [10,] "9.38" "23.7" "3" "-0.999754311749369" "0.999508683861454" #> [11,] "9.03" "24.08" "3" "-0.999999127979356" "0.999998255959473" #> [12,] "9.03" "24.15" "3" "-0.999698355328196" "0.9993968016459" #> R2ADJ AUCLST AUCALL AUCIFO #> [1,] "0.999999459349959" "148.92305" "148.92305" "216.611933038226" #> [2,] "0.995793082425955" "91.5268" "91.5268" "100.173459143183" #> [3,] "0.998649923698427" "99.2865" "99.2865" "109.535970740547" #> [4,] "0.997848274051385" "106.7963" "106.7963" "118.378881427603" #> [5,] "0.997970776874129" "121.2944" "121.2944" "139.419777837118" #> [6,] "0.99788960458362" "73.77555" "73.77555" "84.2544183301878" #> [7,] "0.998005251479131" "90.7534" "90.7534" "103.771801796293" #> [8,] "0.988765489283318" "88.55995" "88.55995" "103.906686815243" #> [9,] "0.998887329645677" "86.32615" "86.32615" "99.9087179279482" #> [10,] "0.999017367722909" "138.3681" "138.3681" "170.652060635217" #> [11,] "0.999996511918946" "80.0936" "80.0936" "89.1027449234385" #> [12,] "0.998793603291801" "119.9775" "119.9775" "130.588831558118" #> AUCIFOD AUCIFP AUCIFPD #> [1,] "0.676912290744456" "216.614955803818" "0.67692173688693" #> [2,] "0.313042059822447" "100.064317640308" "0.312700992625963" #> [3,] "0.342299908564208" "109.585721753278" "0.342455380478994" #> [4,] "0.369934004461258" "118.44355857992" "0.370136120562249" #> [5,] "0.435686805740995" "139.254630430615" "0.435170720095671" #> [6,] "0.263295057281837" "84.4966985785753" "0.264052183058048" #> [7,] "0.324286880613414" "103.893147024686" "0.324666084452144" #> [8,] "0.324708396297635" "103.643051464786" "0.323884535827455" #> [9,] "0.312214743524838" "99.8660676588793" "0.312081461433998" #> [10,] "0.533287689485054" "170.567912545332" "0.533024726704162" #> [11,] "0.278446077885745" "89.1007189855217" "0.278439746829755" #> [12,] "0.408090098619118" "130.639068046815" "0.408247087646298" #> AUCPEO AUCPEP AUMCLST AUMCIFO #> [1,] "31.2489169404534" "31.2498763313113" "1459.0711035" "4505.53481941065" #> [2,] "8.63168669340252" "8.53203003991598" "706.586566" "999.772287999786" #> [3,] "9.3571734209797" "9.39832451573008" "803.18587" "1150.96476871455" #> [4,] "9.7843308603032" "9.83359392402986" "901.0842105" "1303.25240140958" #> [5,] "13.0005786254328" "12.8974026752838" "1017.1143165" "1667.72161189007" #> [6,] "12.4371736674055" "12.688245527848" "609.1523875" "978.428485741731" #> [7,] "12.5452209279821" "12.6473664538854" "782.41986" "1245.09840831465" #> [8,] "14.7697297311878" "14.5529307094073" "739.534598" "1298.11575468474" #> [9,] "13.5949777052926" "13.5580763078894" "705.2296255" "1201.77153812025" #> [10,] "18.9180022292417" "18.8780011813617" "1278.180042" "2473.99342735889" #> [11,] "10.1109622730249" "10.1089184106194" "617.2422125" "928.559971386069" #> [12,] "8.12575733430562" "8.16108703637935" "977.8807235" "1330.38400236898" #> AUMCIFP AUMCPEO AUMCPEP #> [1,] "4505.67086458209" "67.6160286851172" "67.6170064935417" #> [2,] "996.071583509104" "29.3252499112927" "29.0626720309864" #> [3,] "1152.65289026304" "30.2162940315685" "30.318495985664" #> [4,] "1305.4981091996" "30.8588106551423" "30.9777467963968" #> [5,] "1661.79367436228" "39.011744571249" "38.7941877387202" #> [6,] "986.966459689532" "37.7417566662308" "38.280335514986" #> [7,] "1249.41106012833" "37.1599983764277" "37.376906210544" #> [8,] "1288.52011616077" "43.0301500208197" "42.605894256157" #> [9,] "1200.2123597462" "41.3174964516894" "41.2412628670872" #> [10,] "2470.87654175199" "48.3353501320931" "48.2701777931124" #> [11,] "928.489963582081" "33.5269415524517" "33.5219295081337" #> [12,] "1332.05283411623" "26.4963558071417" "26.5884431567018" #> MRTEVLST MRTEVIFO MRTEVIFP #> [1,] "9.79748335465867" "20.8000305256292" "20.8003683211179" #> [2,] "7.71999639449866" "9.98041094468705" "9.95431345556755" #> [3,] "8.08957783787323" "10.5076420187191" "10.5182762117325" #> [4,] "8.43741038313125" "11.0091630001303" "11.0221115006327" #> [5,] "8.38550103302378" "11.9618725389051" "11.9334895308224" #> [6,] "8.25683288704727" "11.612785479182" "11.6805328053348" #> [7,] "8.62138344128154" "11.9984271908357" "12.0259237101698" #> [8,] "8.3506663903943" "12.4930915850769" "12.4322865638375" #> [9,] "8.1693626496722" "12.0286954236259" "12.0182198807093" #> [10,] "9.23753409926132" "14.4972959491374" "14.4861744795951" #> [11,] "7.70651103833515" "10.4212274513421" "10.4206786898426" #> [12,] "8.15053425433936" "10.1875787270284" "10.1964355229393" #> VZFO VZFP CLFO #> [1,] "30.4867482345887" "30.4863228055447" "1.47729626669981" #> [2,] "30.6904415765423" "30.7239160557228" "3.19445891892989" #> [3,] "28.5170999496524" "28.5041534217657" "2.92141474473231" #> [4,] "27.2259641330176" "27.2110971545992" "2.70318485984093" #> [5,] "26.4979946505636" "26.5294196385914" "2.29522672438806" #> [6,] "43.2597344953234" "43.135694392041" "3.79802040465035" #> [7,] "34.9084408430805" "34.8676684452056" "3.08368934971535" #> [8,] "37.8105081118408" "37.9066861615621" "3.07968630131565" #> [9,] "38.8427934436931" "38.8593822173436" "3.20292369511514" #> [10,] "25.0155401378403" "25.0278813214113" "1.87516048038837" #> [11,] "37.6221852019531" "37.6230406407462" "3.59135961832556" #> [12,] "22.2242935639128" "22.2157473419508" "2.4504392617801" #> CLFP #> [1,] "1.47727565168591" #> [2,] "3.19794315842211" #> [3,] "2.92008844656286" #> [4,] "2.70170876184947" #> [5,] "2.29794872178016" #> [6,] "3.78713021198604" #> [7,] "3.08008765894795" #> [8,] "3.08752005539633" #> [9,] "3.20429158273309" #> [10,] "1.87608557333405" #> [11,] "3.59144127728081" #> [12,] "2.44949695970983" #> attr(,"units") #> [1] "" "" "mg/L" "mg/L/mg" "h" "h" #> [7] "mg/L" "mg/L" "h" "h" "/h" "h" #> [13] "h" "" "" "" "" "h*mg/L" #> [19] "h*mg/L" "h*mg/L" "h*mg/L/mg" "h*mg/L" "h*mg/L/mg" "%" #> [25] "%" "h2*mg/L" "h2*mg/L" "h2*mg/L" "%" "%" #> [31] "h" "h" "h" "L" "L" "L/h" #> [37] "L/h"tblNCA(Indometh, key="Subject", colTime="time", colConc="conc", dose=25, adm="Infusion", dur=0.5, concUnit="mg/L")#> ID b0 CMAX CMAXD TMAX TLAG CLST #> [1,] "1" "-1.72421059639646" "1.5" "0.06" "0.25" "0" "0.05" #> [2,] "2" "-0.175286858431038" "2.03" "0.0812" "0.25" "0" "0.08" #> [3,] "3" "0.155579544657487" "2.72" "0.1088" "0.25" "0" "0.08" #> [4,] "4" "0.0643586275963175" "1.85" "0.074" "0.25" "0" "0.07" #> [5,] "5" "-0.982357129866236" "2.05" "0.082" "0.25" "0" "0.06" #> [6,] "6" "-0.0499189799474626" "2.31" "0.0924" "0.25" "0" "0.09" #> CLSTP TLST LAMZHL LAMZ LAMZLL #> [1,] "0.0502485064135143" "8" "4.37812701206528" "0.158320482400297" "5" #> [2,] "0.0747559092002026" "8" "2.293063170278" "0.302280019819912" "0.75" #> [3,] "0.0399725765960521" "8" "1.64294680807057" "0.421892648718165" "0.5" #> [4,] "0.0344498520872912" "8" "1.61544094217238" "0.429076150334429" "0.5" #> [5,] "0.0495714902818329" "8" "2.74244612209262" "0.252747784168332" "1" #> [6,] "0.0562424678832525" "8" "1.9606985693831" "0.353520521401732" "0.75" #> LAMZUL LAMZNPT CORRXY R2 #> [1,] "8" "3" "-0.998532286621828" "0.997066727426216" #> [2,] "8" "9" "-0.973482979595454" "0.947669111562043" #> [3,] "8" "10" "-0.935855785859431" "0.875826051926574" #> [4,] "8" "10" "-0.931191674546507" "0.867117934744728" #> [5,] "8" "8" "-0.935544879811905" "0.875244222142273" #> [6,] "8" "9" "-0.950764854539454" "0.903953808627429" #> R2ADJ AUCLST AUCALL AUCIFO #> [1,] "0.994133454852432" "1.74125" "1.74125" "2.05706510643443" #> [2,] "0.94019327035662" "2.9325" "2.9325" "3.19715526913642" #> [3,] "0.860304308417395" "2.93375" "2.93375" "3.12337169699582" #> [4,] "0.850507676587818" "2.4775" "2.4775" "2.64064120452848" #> [5,] "0.854451592499318" "1.95375" "1.95375" "2.19114080521489" #> [6,] "0.890232924145633" "2.8725" "2.8725" "3.12708210924544" #> AUCIFOD AUCIFP AUCIFPD #> [1,] "0.0822826042573772" "2.0586347480231" "0.0823453899209241" #> [2,] "0.127886210765457" "3.17980681586146" "0.127192272634459" #> [3,] "0.124934867879833" "3.02849584759299" "0.121139833903719" #> [4,] "0.105625648181139" "2.55778843379069" "0.102311537351628" #> [5,] "0.0876456322085957" "2.14988026656177" "0.085995210662471" #> [6,] "0.125083284369817" "3.0315925122543" "0.121263700490172" #> AUCPEO AUCPEP AUMCLST AUMCIFO #> [1,] "15.3527034922993" "15.4172442842464" "3.27125" "7.79255448051925" #> [2,] "8.2778359778536" "7.77741637095222" "6.39875" "9.39152229661219" #> [3,] "6.07105767072826" "3.12847870233298" "5.00625" "6.97267842561125" #> [4,] "6.17809054288414" "3.13897868682219" "4.381875" "6.06721967358498" #> [5,] "10.83411913328" "9.12284603065077" "3.7075" "6.54586634839538" #> [6,] "8.14120321601879" "5.24781980464785" "5.5325" "8.28929076671746" #> AUMCIFP AUMCPEO AUMCPEP #> [1,] "7.81502594373644" "58.0208260567461" "58.1415337127341" #> [2,] "9.19534267578028" "31.8667432402495" "30.4131425481974" #> [3,] "5.9887901357925" "28.2019090166038" "16.4063210350329" #> [4,] "5.21130178173009" "27.7778746156581" "15.915923054733" #> [5,] "6.05253416426272" "43.3612022813628" "38.7446662938147" #> [6,] "7.25526351286615" "33.2572573975366" "23.7450164258139" #> MRTIVLST MRTIVIFO MRTIVIFP #> [1,] "1.62867910983489" "3.53819049340947" "3.54621783380523" #> [2,] "1.93201193520887" "2.68746205799662" "2.64179286927502" #> [3,] "1.45643374520665" "1.98242031434102" "1.72748005517403" #> [4,] "1.51866801210898" "2.04763122047032" "1.78742487567935" #> [5,] "1.64763275751759" "2.73742387199229" "2.56528895278541" #> [6,] "1.6760226283725" "2.40080687910611" "2.14321857523362" #> VZO VZP CLO #> [1,] "76.7635174614967" "76.7049877929306" "12.1532371152478" #> [2,] "25.8682374307925" "26.0093698751079" "7.81945132328614" #> [3,] "18.9720552210259" "19.5664063261934" "8.00417062882588" #> [4,] "22.0646090817291" "22.7793335575756" "9.46739752342239" #> [5,] "45.1421630553333" "46.0085322167232" "11.409581684801" #> [6,] "22.61445337783" "23.3267671305837" "7.99467334934562" #> CLP VSSO VSSP #> [1,] "12.1439706698857" "43.0004680253208" "43.0651653627562" #> [2,] "7.86211284135105" "21.0144787456829" "20.7700736417167" #> [3,] "8.2549229908536" "15.8676304540362" "14.2602148236972" #> [4,] "9.7740687500684" "19.3857387455631" "17.4704136204725" #> [5,] "11.6285545706141" "31.2328612734204" "29.8306025768587" #> [6,] "8.24649087862073" "19.1936667733153" "17.6740324315546" #> attr(,"units") #> [1] "" "" "mg/L" "mg/L/mg" "h" "h" #> [7] "mg/L" "mg/L" "h" "h" "/h" "h" #> [13] "h" "" "" "" "" "h*mg/L" #> [19] "h*mg/L" "h*mg/L" "h*mg/L/mg" "h*mg/L" "h*mg/L/mg" "%" #> [25] "%" "h2*mg/L" "h2*mg/L" "h2*mg/L" "%" "%" #> [31] "h" "h" "h" "L" "L" "L/h" #> [37] "L/h" "L" "L"