Calculate descriptive statistics of simulated pharmacokinetic parameters

caffDescstat will calculate descriptive statistics of simulated PK parameters

caffDescstat(caffPkparamData)

Arguments

caffPkparamData	data frame generated by caffPkparam function

Value

The descriptive statistics of pharmacokinetic parameters

See also

https://asancpt.github.io/caffsim

Examples

caffDescstat(caffPkparam(20,500))
#> # A tibble: 8 x 2
#>   `PK parameters` `value: mean (sd) [min-max]`   
#>   <chr>           <chr>                          
#> 1 AUC             305.90 (132.21) [153.55-629.94]
#> 2 CL              1.91 (0.75) [0.79-3.26]        
#> 3 Cmax            30.84 (7.99) [19.27-51.49]     
#> 4 Half_life       6.04 (1.98) [3.59-12.06]       
#> 5 Ka              7.89 (9.07) [1.02-37.12]       
#> 6 Ke              0.12 (0.03) [0.06-0.19]        
#> 7 Tmax            1.02 (0.69) [0.15-2.36]        
#> 8 V               15.14 (3.32) [9.40-22.26]      
caffDescstat(caffPkparamMulti(20,500))
#> # A tibble: 8 x 2
#>   `PK parameters` `value: mean (sd) [min-max]`   
#>   <chr>           <chr>                          
#> 1 Aavss           497.69 (152.79) [269.34-807.29]
#> 2 AI              1.59 (0.28) [1.19-2.17]        
#> 3 AUCS            279.43 (124.04) [111.83-497.41]
#> 4 Cavss           34.93 (15.50) [13.98-62.18]    
#> 5 CmaxS           30.88 (7.40) [17.44-45.92]     
#> 6 Cmaxss          54.99 (18.70) [25.55-85.13]    
#> 7 Cminss          20.81 (12.33) [5.31-44.93]     
#> 8 TmaxS           0.81 (0.68) [0.16-2.60]        
caffDescExample <- cbind(caffDescstat(caffPkparam(20,500)),
                         caffDescstat(caffPkparam(50,500))[,2])
colnames(caffDescExample)[2:3] <- c('20 kg', '50 kg')
caffDescExample
#>   PK parameters                          20 kg                         50 kg
#> 1           AUC 254.35 (98.78) [134.98-510.81] 130.33 (69.53) [61.84-351.74]
#> 2            CL        2.21 (0.71) [0.98-3.70]       4.70 (1.97) [1.42-8.09]
#> 3          Cmax     27.74 (6.07) [18.59-39.50]     14.24 (2.98) [8.02-20.59]
#> 4     Half_life        5.35 (1.46) [3.08-8.47]      5.39 (2.13) [3.31-12.34]
#> 5            Ka       5.28 (6.49) [0.74-26.00]      6.68 (6.84) [0.87-25.38]
#> 6            Ke        0.14 (0.04) [0.08-0.22]       0.14 (0.04) [0.06-0.21]
#> 7          Tmax        1.29 (0.81) [0.20-3.27]       1.03 (0.69) [0.19-2.38]
#> 8             V     15.90 (3.14) [11.12-22.00]    32.06 (6.81) [22.19-47.38]