Create a concentration-time dataset of multiple oral dosing of caffeine

caffConcTimeMulti will create a dataset of the concentration-time curve of multiple oral administration of caffeine.

caffConcTimeMulti(Weight, Dose, N = 20, Tau = 8, Repeat = 4)

Arguments

Weight	Body weight (kg)
Dose	Dose of single caffeine (mg)
N	The number of simulated subjects
Tau	The interval of multiple dosing (hour)
Repeat	The number of dosing

Value

The dataset of concentration and time of simulated subjects of multiple dosing

See also

https://asancpt.github.io/caffsim

Examples

caffConcTimeMulti(Weight = 20, Dose = 200, N = 20, Tau = 8, Repeat = 4)
#> # A tibble: 19,220 x 3
#> # Groups:   Subject [20]
#>    Subject  Time  Conc
#>      <dbl> <dbl> <dbl>
#>  1       1   0    0   
#>  2       1   0.1  9.67
#>  3       1   0.2  9.89
#>  4       1   0.3  9.76
#>  5       1   0.4  9.63
#>  6       1   0.5  9.49
#>  7       1   0.6  9.35
#>  8       1   0.7  9.22
#>  9       1   0.8  9.09
#> 10       1   0.9  8.96
#> # ... with 19,210 more rows
caffConcTimeMulti(20, 200)
#> # A tibble: 19,220 x 3
#> # Groups:   Subject [20]
#>    Subject  Time  Conc
#>      <dbl> <dbl> <dbl>
#>  1       1   0    0   
#>  2       1   0.1  3.01
#>  3       1   0.2  5.56
#>  4       1   0.3  7.71
#>  5       1   0.4  9.54
#>  6       1   0.5 11.1 
#>  7       1   0.6 12.3 
#>  8       1   0.7 13.4 
#>  9       1   0.8 14.3 
#> 10       1   0.9 15.0 
#> # ... with 19,210 more rows