ncar-package: Noncompartmental Analysis for Pharmacokinetic Report

Description

It can report a noncompartmental analysis (NCA) with industrial strength.

Details

The main functions are

  • pdfNCA to produce PDF file format NCA.
  • rtfNCA to produce rtf file format NCA.

Author

Kyun-Seop Bae

References

  • Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016.

  • Shargel L, Yu A. Applied Biopharmaceutics and Pharmacokinetics. 7th ed. 2015.

  • Rowland M, Tozer TN. Clinical Pharmacokinetics and Pharmacodynamics - Concepts and Applications. 4th ed. 2011.

  • Gibaldi M, Perrier D. Pharmacokinetics. 2nd ed. revised and expanded. 1982.

Examples

 # Theoph and Indometh data: dose in mg, conc in mg/L, time in h
 
 # Output to PDF file
 #pdfNCA(fileName="NCA-Theoph.pdf", Theoph, key="Subject", colTime="Time",
 #       colConc="conc", dose=320, doseUnit="mg", timeUnit="h", concUnit="mg/L")
 #pdfNCA(fileName="NCA-Theoph.pdf", Theoph, key=c("Subject", "Wt"), colTime="Time",
 #       colConc="conc", dose=320, doseUnit="mg", timeUnit="h", concUnit="mg/L")
 #pdfNCA(fileName="NCA-Indometh.pdf", Indometh, key="Subject", colTime="time",
 #       colConc="conc", adm="Infusion", dur=0.5, dose=25, doseUnit="mg",
 #       timeUnit="h", concUnit="mg/L")
 
 
 # Output to RTF file
 #rtfNCA(fileName="NCA-Theoph.rtf", Theoph, key="Subject", colTime="Time",
 #       colConc="conc", dose=320, doseUnit="mg", timeUnit="h", concUnit="mg/L")
 #rtfNCA(fileName="NCA-Theoph.rtf", Theoph, key=c("Subject", "Wt"), colTime="Time",
 #       colConc="conc", dose=320, doseUnit="mg", timeUnit="h", concUnit="mg/L")
 #rtfNCA(fileName="NCA-Indometh.rtf", Indometh, key="Subject", colTime="time",
 #       colConc="conc", adm="Infusion", dur=0.5, dose=25, doseUnit="mg",
 #       timeUnit="h", concUnit="mg/L")